ubiquity: PKPD, PBPK, and Systems Pharmacology Modeling Tools

Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint'.

Version: 1.0.0
Imports: deSolve, digest, doParallel, doRNG, flextable, foreach, gridExtra, grid, gdata, ggplot2, knitr, MASS, officer (≥ 0.3.5), optimx, PKNCA, pso, rmarkdown, rhandsontable, rstudioapi, stats, shiny
Suggests: GA, GGally, gridGraphics, webshot, testthat, ggrepel
Published: 2019-10-17
Author: John Harrold [aut, cre]
Maintainer: John Harrold <john.m.harrold at gmail.com>
BugReports: https://github.com/john-harrold/ubiquity/issues
License: BSD_2_clause + file LICENSE
URL: https://ubiquity.tools/rworkflow
NeedsCompilation: no
SystemRequirements: Perl
Materials: README
CRAN checks: ubiquity results

Downloads:

Reference manual: ubiquity.pdf
Vignettes: Deployment
Estimation
Language
NCA
Reporting
Simulation
Titration
Package source: ubiquity_1.0.0.tar.gz
Windows binaries: r-devel: ubiquity_1.0.0.zip, r-devel-gcc8: ubiquity_1.0.0.zip, r-release: ubiquity_1.0.0.zip, r-oldrel: ubiquity_1.0.0.zip
OS X binaries: r-release: ubiquity_1.0.0.tgz, r-oldrel: ubiquity_1.0.0.tgz

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